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1 article(s) from Mansour, Randa SH.

Ciprofloxacin-loaded dissolving polymeric microneedles as a potential therapeutic for the treatment of S. aureus skin infections

Sharif Abdelghany,
Walhan Alshaer,
Yazan Al Thaher,
Maram Al Fawares,
Amal G. Al-Bakri,
Saja Zuriekat and
Randa SH. Mansour

Beilstein J. Nanotechnol. 2022, 13, 517–527, doi:10.3762/bjnano.13.43

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Figure 1: Microneedle fabrication using the two-layer centrifugation method. PVA/PVP or PVA gel with ciproflo...

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Figure 2: Schematic presentation of the skin deposition study of CIP_MN1. The full-thickness human skin was e...

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Figure 3: In vitro model for the antimicrobial activity of CIP_MN1. Preincubated inoculum of S. aureus is str...

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Figure 4: Microneedle visualization for two formulations; (a) CIP_MN1 images under digital light microscope, ...

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Figure 5: (a) Parafilm penetration with CIP_MN1 microneedles; (b) artificial skin (agarose-based) penetration...

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Figure 6: (a) CIP_MN1 dissolution in excised human skin over time (represented by CIP_MN1 height decease with...

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Figure 7: Ciprofloxacin skin deposition from CIP_MN1 after 1 h and 12 h from insertion, and from free gel aft...

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Figure 8: Antibacterial activity of CIP_MN1 applied on an in vitro skin model mounted on S. aureus-inoculated...

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Published 15 Jun 2022

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